Florence Mongin

Head of CORINT - UR1 Professor

Florence Mongin
Univ Rennes, CNRS, ISCR (Institut des Sciences Chimiques de Rennes)-UMR 6226

Campus de Beaulieu, Bâtiment 10, Avenue du Général Leclerc, F-35000 Rennes



Email : florence [dot] mongin [at] univ-rennes [dot] fr

Phone : +33 (0) 2 23 23 69 31

Office number : Beaulieu 10A, Office 018

Scientific skills

• Aromatic heterocycles
• Stereoselective syntheses of ferrocene derivatives
• Bimetallic bases

Education and professional experience

• Professor (2005-), Université de Rennes, Institut des Sciences Chimiques de Rennes, UMR 6226 (France)
• Junior member of the Institut Universitaire de France (2009-2014)
• D. Sc. in Chemistry (Habilitation à Diriger des Recherches, 2003), Université de Rouen (France)
• Assistant-professor (1997-2004), Université de Rouen, Institut de Recherche en Chimie Organique Fine, UMR CNRS 6014 (France)
• Post-doctoral fellow (1995-1997), Institute of organic Chemistry, University of Lausanne (Switzerland)
• PhD (1991-1994), Université de Rouen (France)

Main present international collaborations

• Ghenia Bentabed-Ababsa, Oran (Algeria)
• Yury Halauko, Minsk (Byelorussia)
• Stefan Knapp, Frankfurt (germany)
• Masanobu Uchiyama and Yu Kitazawa, RIKEN, University Tokyo & Nagano (Japan)

Scientific Production


Florence Mongin studied Chemistry at the Université de Rouen where she obtained her PhD in 1994 under the supervision of Prof. Guy Quéguiner. After a two-year postdoctoral position at the Institute of Organic Chemistry of Lausanne with Prof. Manfred Schlosser, she returned to the University of Rouen as an Assistant Professor in 1997 (habilitation in 2003). She took up her present position in 2005 as Professor at the University of Rennes, and has been appointed Junior member of the Institut Universitaire de France from 2009 to 2014.

She is skilled in the functionalization of aromatic compounds including heterocycles, and in particular by using lithium bases or bimetallic complexes and combinations. Her present scientific interests also include the implementation of aromatic heterocycles to reach molecules of biological interest.

Selected Publications

1Oxazolo[5,4-f]quinoxaline-type selective inhibitors of glycogen synthase kinase-3α (GSK-3α): Development and impact on temozolomide treatment of glioblastoma cells.
Hasyeoui, M.; Lassagne, F.; Erb, William; Nael, M.; Elokely, K. M.; Chaikuad, A.; Knapp, S.; Jorda, A.; Vallés, S. L.; Quissac, E.; Verreault, M.; Robert, T.; Bach, S.; Samarat, A.; Mongin, F. Bioorg. Chem. 2023, 97, 106456.
2From ferrocene to decasubstituted enantiopure ferrocene-1,1’-disulfoxide derivatives.
Wen, M.; Erb, W.; Mongin, F.; Hurvois, J.-P.; Halauko, Y. S.; Ivashkevich, O. A.; Matulis, V. E.; Blot, M.; Roisnel, T. Dalton Trans. 2023, 52, 3725-3737.
3From benzofuro-, benzothieno- and 10-methylindolo- [2,3-b]-fused benzothiopyrano[4,3,2-de]quinolines to the corresponding benzothiopyrano[4,3,2-de]1,8-naphthyridines: Synthesis and properties of these hexacyclic heteroaromatic compounds.
Mast, N.; Erb, W.; Nauton, L.; Moreau, P.; Mongin, O.; Roisnel, T.; Macaigne, M.; Robert, T.; Bach, S.; Picot, L.; Thiéry, V.; Hurvois, J.-P.; Mongin, F. New J. Chem. 2023, 47, 258-283.
4Halogen dance on 2-iodobenzofuran and 2-iodobenzothiophene and related reactions.
Elmir, L.; Bentabed-Ababsa, G.; Erb, W.; Roisnel, T.; Mongin, F. Eur. J. Org. Chem. 2023, e202300024.
5Enantioselective deprotometalation of alkyl ferrocenecarboxylates using bimetallic bases.
Dayaker, G.; Erb, W.; Hedidi, M.; Chevallier, F.; Blot, M.; Gros, P. C.; Hilmersson, G.; Roisnel, T.; Dorcet, V.; Bentabed-Ababsa, G.; Mongin, F. New J. Chem. 2021, 45, 22579-22590.
6Functionalization of 9-thioxanthone at the 1-position: from arylamino derivatives to [1]benzo(thio)pyrano[4,3,2-de]benzothieno[2,3-b]quinolines of biological interest.
Mokhtari Brikci-Nigassa, N.; Nauton, L.; Moreau, P.; Mongin, O.; Duval, R. E.; Picot, L.; Thiéry, V.; Souab, M.; Baratte, B.; Ruchaud, S.; Bach, S.; Le Guevel, R.; Bentabed-Ababsa, G.; Erb, W.; Roisnel, T.; Dorcet, V.; Mongin, F. Bioorg. Chem. 2020, 94, 103347.

Publications: 166

Publications Referenced in HAL :